CureVac is pioneering the use of natural and chemically unmodified mRNA as a data carrier to instruct the human body to produce its own proteins capable of fighting a wide range of diseases. CureVac’s novel technology is the broadest and most advanced mRNA therapeutic platform and allows for rapid, low-cost production of multiple drugs and vaccines. Additionally, CureVac’s mRNA vaccines are thermostable, which eliminates the demand for cold-chain storage and infrastructure, a major challenge in the vaccine supply of most developing countries.
CureVac’s RNA Technology – Inspired by Nature
CureVac’s active ingredients do not negatively manipulate the body, but rather work based on the very same functional principles found in nature. Our format is simple: the body receives specific information that is coded in RNA and uses this information to produce its own, custom-tailored protein as medicine.
After CureVac’s founding in 2000, we developed several technology platforms with which we specifically formulate and use RNA as the basic molecule in different ways.
Versatile RNA Technology Platforms
- RNActive® – developed based on optimized, antigen-encoding and complexed mRNA molecules – stimulates the immune system, thereby providing potent vaccines for the prevention of infectious diseases or supplying potent novel immunotherapies against cancer.
- RNArt® is our novel mRNA-based approach in the field of molecular therapy. The technology is designed to trigger the body’s own production of desired proteins for therapeutic purposes.
- RNAdjuvant® – developed based on long-chain, non-coding RNA molecules – improves the quantity and quality of the immune response, thereby amplifying the effects of immunotherapeutic treatments against cancer or of conventional vaccines used to prevent infectious diseases.
In-House, GMP Production Facility
In addition to generating our own technology platforms, CureVac maintains its own in-house, GMP (Good Manufacturing Practice)-compliant, cleanroom pharmaceutical production facility. We are able to manufacture all of the optimized RNA-based active ingredients that we have developed.
PureMessenger® is a process developed by CureVac in which RNA is produced with a specifically desired composition and amount in an extremely pure form.